nitial dosages in dogs are 3-5mg/kg q8-12h but have been increased up to 12mg/kg q8h. If one is converting a patient from primidone to phenobarbital or vice versa, the conversion is 65mg phenobarbital to 250mg primidone.
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The initial dose for the dog is 3-5 milligrams per kilogram every 8-12 hours. Doses of up to 12 milligrams per kilogram every 8 hours have been used.
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If a patient is to be switched from primidone to phenobarbital, or vice versa, 65 milligrams of phenobarbital has activity equivalent to 250 milligrams of primidone.