Difference between revisions of "Leptospirosis - Cats and Dogs"

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==Description==
  
 
**Dogs and cats
 
**Dogs and cats
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*method of action
 
*method of action
 
**cause anaemia via intravascular haemolysis
 
**cause anaemia via intravascular haemolysis
=====Clinical=====
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==Signalment==
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==Diagnosis==
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===Clinical Signs===
 
*fever
 
*fever
 
*dehydration
 
*dehydration
 
*haemorrhaging from the mucous membranes of the body
 
*haemorrhaging from the mucous membranes of the body
=====Diagnosis=====
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 +
===Laboratory Tests===
 
*dark field microscopy on fresh urine is best
 
*dark field microscopy on fresh urine is best
=====Gross=====
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===Pathology===
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Grossly-
 
*widespread hameorrhages
 
*widespread hameorrhages
 
*icterus
 
*icterus
 
*pale foci in the [[Liver - Anatomy & Physiology|liver]] (not always a constant finding)
 
*pale foci in the [[Liver - Anatomy & Physiology|liver]] (not always a constant finding)
 
*subcapsular and cortical renal haemorrhages
 
*subcapsular and cortical renal haemorrhages
=====Microscopically=====
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<br>
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Microscopically-
 
*foci of necrosis
 
*foci of necrosis
 
*dissociation of hepatocytes form each other (similar to post mortem change)
 
*dissociation of hepatocytes form each other (similar to post mortem change)
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*need to use a silver stain or immunofluorescence to demonstrate the organisms in tissues
 
*need to use a silver stain or immunofluorescence to demonstrate the organisms in tissues
  
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==Treatment==
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==Prognosis==
  
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==References==
  
 
[[Category:Cat]][[Category:Dog]]
 
[[Category:Cat]][[Category:Dog]]
 
[[Category:Hepatitis,_Bacterial]]
 
[[Category:Hepatitis,_Bacterial]]
 
[[Category:To_Do_-_lizzyk]]
 
[[Category:To_Do_-_lizzyk]]

Revision as of 08:53, 2 September 2010




Description

    • Dogs and cats
      • Serovars canicola and icterohaemorrhagica cause leptospirosis in dogs, but are vaccinated against
      • Serovars pomona and grippotyphosa are becoming important
      • The host-adapted serovar canicolar causes acute renal failure in puppies; a chronic uraemic syndrome may follow
      • Incidental infections with serovar icterohaemorrhagica or copenhagenii cause renal failure
      • L. icterohaemorrhagiae may cause hepatic jaundice
      • Serovar bratislava causes abortion and infertility in dogs, which may be the maintenance host
      • Infections uncommon in cats


  • Leptospirosis icterohaemorrhagica - a septicaemic disease which affects the liver
  • puppies
  • Leptospirosis is an important spirochaetal group of diseases causing disease in animals and humans (zoonotic)
  • Transmission
    • via urine of affected animals
    • organisms can remain viable for weeks in damp conditions
  • method of action
    • cause anaemia via intravascular haemolysis

Signalment

Diagnosis

Clinical Signs

  • fever
  • dehydration
  • haemorrhaging from the mucous membranes of the body

Laboratory Tests

  • dark field microscopy on fresh urine is best

Pathology

Grossly-

  • widespread hameorrhages
  • icterus
  • pale foci in the liver (not always a constant finding)
  • subcapsular and cortical renal haemorrhages


Microscopically-

  • foci of necrosis
  • dissociation of hepatocytes form each other (similar to post mortem change)
  • substantial haemosiderin in the Kuppfer cells (from the haemolysis)
  • need to use a silver stain or immunofluorescence to demonstrate the organisms in tissues

Treatment

Prognosis

References