Changes

===Pathology===

===Pathology===

Grossly-

Grossly-

*widespread hameorrhages

* Widespread hameorrhages

*icterus

* Icterus

*pale foci in the [[Liver - Anatomy & Physiology|liver]] (not always a constant finding)

* Pale foci in the [[Liver - Anatomy & Physiology|liver]] (not always a constant finding)

*subcapsular and cortical renal haemorrhages

* Subcapsular and cortical renal haemorrhages

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Microscopically-

Microscopically-

*foci of necrosis

* Foci of necrosis

*dissociation of hepatocytes form each other (similar to post mortem change)

* Dissociation of hepatocytes

*substantial haemosiderin in the Kuppfer cells (from the haemolysis)

* Substantial haemosiderin in the Kuppfer cells

*need to use a silver stain or immunofluorescence to demonstrate the organisms in tissues

* A silver stain or immunofluorescence will demonstrate the organisms in tissues

==Treatment==

==Treatment==

Doxycyclin is the antibiotic of choice for treating leptospirosis as it also targets the renal carrier phase, preventing transmission of the disease.  

Doxycyclin is the antibiotic of choice for treating leptospirosis as it also targets the renal carrier phase, preventing transmission of the disease.  

==References==

==References==

[[Category:Hepatitis,_Bacterial]]

[[Category:Hepatitis,_Bacterial]]

[[Category:To_Do_-_lizzyk]]

[[Category:To_Do_-_lizzyk]]