Angiotensin Converting Enzyme

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ACE

  • Membrane bound metalloproteinase
  • Converts Angiotensin 1 to Angiotensin 2
  • Very important in the Renin Angiotensin Aldosterone System (RAAS)
  • Predominantly expressed on epithelial cell membranes in the pulmonary ciculation
  • The site of action of the group of drugs - ACE inhibitors