Sex Hormones
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Sex hormones are produced by the zona reticularis of the adrenal glands in addition to those produced by the ovary and testis:
- Testis: Produces androgens:
- Increase mitoses in skin.
- Increase sebaceous secrretion.
- Increase hair growth.
- Ovary: Produces oestrogens and progesterone. Effects of oestrogens include:
- Decreased collagen production.
- Decreased sebaceous secretion.
- Decreased epidermal thickness.
- Decreased hair growth.
- Increased skin pigmentation.
Hyperoestrogenism
Females
Ovarian Imbalance Type 1 Seen in adult bitches who present with alopecia and increased pigmentation round the perianal, perigenital and axillary areas. Caused by:
- Cystic ovaries.
- Ovarian neoplasia.
Males
Dogs present with bilaterally symmetric alopecia, similar hyperpigmentation to that seen with female dogs with ovarian imbalance, loss of libido and gynaecomastia. The dogs become attractive to other male dogs. Caused by: