Category:Liver - Degenerative Pathology

Equine Hyperlipidaemia

Ovine White Liver Disease

associated with derangement of carbohydrate metabolism

Diabetes mellitus

Ketosis

• due to an excessive drain on carbohydrate stores because pregnant and lactating animals have a continuous demand for glucose
• ketosis results when fat metabolism which occurs in response to the increased energy demand is excessive
• ketone bodies accumulate in the blood and there is marked fatty change in the liver
• can occur in starvation but commonly seen in two conditions in livestock:

Ketosis of Cattle

Pregnancy Toxaemia

associated with anoxia and toxaemia

anoxia

• passive congestion
• anaemias

toxaemia

• toxins absorbed from the gut interfere with many stages of triglyceride metabolism