Selective IgA deficiency of German Shepherd Dogs

Description

IgA deficiency of German Shepherd dogs is a breed specific lack or reduction of immunoglobulin A caused by a heritable defect inthe immune system. Dogs which are affected are unable to mount an approapriate immune response and more susceptible to infection and alleric conditions.

Signalment

German Shepherd dogs.

References

• Poorly understood
• Linked to other disease syndromes such as deep pyoderma, inflammatory bowel disease, anal furunculosis and disseminated aspergillosis
• IgA deficiency so more susceptible to mucosal disease