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Answer
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Article
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| What is an immunodeficiency?
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- When the immune system fails to protect itself against disease
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| True or False: Primary immunodeficiencies only affect the innate immune system
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- False
- Primary immunodeficiencies can affect both the innate and adaptive immune systems
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| What is Canine Cyclic Haematopoeisis?
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- A primary immunodeficiency
- Also called Grey Collie Syndrome
- Due to an autosomal recessive gene insertion
- Causes cyclic neutropenia every 2 weeks
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| Name two types of Leukocyte Adhesion Deficiency and what type of mutation is the condition caused by?
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- Canine (CLAD)
- Bovine (BLAD)
- Missence mutation
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| Is Severe Combined Immune Deficiency disease (SCID) a primary immunodeficiency of the adaptive or the innate immune system?
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| Which cells are not functioning in animals with SCID?
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| In foals with equine SCID, why does the infection start to develop around 8 weeks of age?
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- Maternal antibodies from the colostrum start to decrease leaving the animal immunocompromised
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| What agents can cause a secondary immunodeficiency?
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- Viruses
- Toxins
- Drugs
- Malnutrition
- Chronic disease
- Stress
- Senescence
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| What is Feline Leukaemia Virus and what does it cause?
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- An oncogenic retrovirus
- Neoplasia
- Myelosuppression
- Immunosuppression
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| How does the FeLV spread in the host?
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- Replicates in the oropharyngeal lymphoid tissue
- Causes a viraemia
- Spreads to the systemic lymphoid system
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| What treatments are available for FeLV?
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- Antibiotics (to treat the secondary infection)
- Anti-retroviral therapy
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| How is FIV mainly spread among cats and which cats are most at risk because of this?
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- Spread mainly by biting
- Cats living outdoors
- Feral tom cats
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