Category:Haemorrhagic Diseases

• There is a wide range of diseases and syndromes that are characterised by haemorrhagic disease.
• Show either:
  • An increased tendency to bleeding - haemorrhagic diathesis.
  • Frank haemorrhages as a clinical feature - purpura.
• Altought this disease is sometimes obvious, it may also be discovered incidentally, for examply following surgery or trauma.

Classification of Haemorrhagic Diseases

• Haemorrhagic diseases may be due to
  1. Increased vessel fragility.
     • Causes non-thrombocytopenic purpura.
  2. Inadequate haemostatic response.
     • This may be caused by:
       • Platelet dysfunction or deficiency.
         • Causes primary or secondary thrombocytopenic purpura.
       • Deficiencies or derangements of clotting factors.
• Syndromes caused by vascular fragility and platelet dysfunction tend to be purpuric and aquired.
• Sydromes caused by clotting factor defects tend to cause more severe bleeding and are usually congenital.

Vascular Fragility

Platelet Abnormalities