Immune Tolerance Flashcards

Immune tolerance

Question	Answer	Article
What is the definition of tolerance?	A state of immune unresponsiveness towards antigens	Link to Answer Article
Where does central tolerance develop?	Thymus	Link to Answer Article
What are the two processes of selection known as?	Positive selection Negative selection	Link to Answer Article
What are the four ways peripheral tolerance can be achieved in T cells?	Ignorance Anergy Cell death Immune deviation/suppression	Link to Answer Article
What is the process in which one T cell response is selectively induced over another?	Immune deviation	Link to Answer Article
What is the definition of tolerance?	A state of immune unresponsiveness towards antigens	Link to Answer Article
What subtype are regulatory T cells?	CD4+	Link to Answer Article
What part of the body do Treg cells develop?	Thymus	Link to Answer Article
What typical inhibitory cytokines do Treg cells secrete?	IL-4 IL-10 TGF-β	Link to Answer Article
The mechanism of suppression of Treg cells depends on the binding of which receptors?	Treg CTLA-4 to target cell B7	Link to Answer Article
What is the transcription repressor unique to Treg cells?	FoxP3	Link to Answer Article