Respiratory Fungal Infections - Pathology
 |
This article has been peer reviewed but is awaiting expert review. If you would like to help with this, please see more information about expert reviewing. |
|
Blastomycosis
Histoplasmosis
Pneumocystis carinii
- Important cause of pneumonia in humans associated with immunodeficiency states
- It has been occasionally reported in young or immunosuppressed animals (e.g. Arabian foals with congenital immunodeficiency)
- Grossly:
- Diffuse interstitial pneumonia
- Patches of firmness or consolidation
- Histologically:
- Alveoli are filled with pale staining acidophilic material (= trophozoite and cyst forms of the organism)
- It is thought that as P. carinii is often present as a latent infection, alveolar macrophages normally control the organism - a process which fails in immunodeficient states