Category:Chronic Inflammation

Types

Granulomatous Inflammation

Granulation Tissue

Granulation tissue (Courtesty of BioMed Archive)
  • Is completlely different to granulomatous inflammation, despite the similarity in name!
  • Occurs on the surface of the skin where large areas of the epithelium have been lost.
  • Makes up the lining of sinus tracts discharging from deeper lesions.
  • Takes its name from the gross appearance of the small vessels which appear at the surface.
    • Look like red granules.
    • These vessels supply inflammatory cells, mainly neutrophils, to the infected surface.
  • The most frequent example in domestic animals is the formation of excessive granulation tissue on the legs of horses with poorly healing wounds.
    • "Proud flesh"
  • Ulcers and open wounds may heal by granulation.

Lymphocytic Inflammation

  • Lymphocytic inflammation is a diffuse chronic ongoing inflammation.
  • Seen in:
    1. Diseases of the central nervous system.
      • Lymphocytes appear microscopically as several layers of cells around blood vessels in the perivascular space.
      • They indicate that there is damage to the nervous tissue further in.
        • Should alert to the possibility of viral infection, which is a common cause of central nervous system disease.
          • E.g. louping ill.
    2. The gut.
      • An excessive number of lymphocytes diffusely infiltrating the lamina propria, often in conjunction with plasma cells, indicate an ongoing non-specific chronic enteritis.
    3. The respiratory tract.
      • Peribronchial and peribronchiolar cuffing may occur to the point of actual lymphoid follicle formation in these areas.
        • Follicles are sometimes large enough to cause partial occlusion of the airways.
      • A feature of some chronic lung diseases.

Pages in category "Chronic Inflammation"

The following 4 pages are in this category, out of 4 total.