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Special:MobileDiff/15014
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Chlamydia and Chlamydophila species
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Revision as of 09:08, 18 May 2008
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09:08, 18 May 2008
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*May cause [[Joints - inflammatory#In Sheep|arthritis in sheep]] and [[Joints - inflammatory#In Cattle|arthritis in cattle]]
*May cause [[Joints - inflammatory#In Sheep|arthritis in sheep]] and [[Joints - inflammatory#In Cattle|arthritis in cattle]]
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===Overview===
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===Characteristics===
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*Obligate intracellular bacteria
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*Gram negative bacteria with outer membrane, LPS, ribosomes, DNA and RNA
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*Peptidoglycan cell wall resistant to lysozyme
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*Only grow in presence of living eukaryotic cells
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*Unable to synthesis ATP therefore require intermediates from host cells
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===Pathogenesis and pathogenicity===
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*Elementary body, the infective form, phagocytosed and internalised into host epithelial cells
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*Transformation into larger reticulate body
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*Reticulate body divides by binary fission to form many new chlamydia cells
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*Reticulate body has un-crosslinked peptidoglycan, which is cross-linked to form elementary bodies
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*Elementary bodies released from dying host cells to infect other cells
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===Clinical infections===
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===Diagnosis===
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===Treatments===
Flawrence
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