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**Absorbed toxin affects neuromuscular junction distant from site of toxin production
**Absorbed toxin affects neuromuscular junction distant from site of toxin production
**Neurotoxin binds irreversibly to ganglioside receptors on motor neurons and is transported to nerve cell body
**Neurotoxin binds irreversibly to ganglioside receptors on motor neurons and is transported to nerve cell body
**Toxins transported to terminals of inhibitory neurons where they block transmission of signals
**Spastic paralysis results
**Toxin can be blood-borne and bind to motor terminals throughout the body as well as in the CNS
*Clinical signs:
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