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*Chief (zygomatic) cells secreting pepsinogen
 
*Chief (zygomatic) cells secreting pepsinogen
    -Secreted in response to vagus and gastrin
+
**Secreted in response to vagus and gastrin
    -Basophilic  
+
**Basophilic  
    -More abundant in base of glands
+
**More abundant in base of glands
 +
**Pepsinogen unfolds and cleaves itself (autocatalyses) in response to hydrochloric acid
 +
**Only active in acidic envrionments
    
[[Image:Fundic region of glandular stomach.jpg|thumb|right|150px|Fundic Region of Glandular Stomach (Parietal and Chief cells)- Copyright RVC 2008]]
 
[[Image:Fundic region of glandular stomach.jpg|thumb|right|150px|Fundic Region of Glandular Stomach (Parietal and Chief cells)- Copyright RVC 2008]]
 
*Goblet cells secreting mucous
 
*Goblet cells secreting mucous
    -Protects against autodigestion
+
**Protects against autodigestion
    
*Parietal (oxyntic) cells secreting hydrochloric acid in gastric pits
 
*Parietal (oxyntic) cells secreting hydrochloric acid in gastric pits
    -Aids digestion
+
**Aids digestion
    -Activates gastric enzymes, e.g. pepsinogen
+
**Activates gastric enzymes, e.g. pepsinogen to pepsin
    -Kills microorganisms that enter with food
+
**Kills microorganisms and enzymes that enter with food
    -Secreted in response to vagus or pepsin   
+
**Secreted in response to vagus or pepsin   
    -Large, pyramid shaped
+
**Large, pyramid shaped
    -More abundant in upper region of glands
+
**More abundant in upper region of glands
    
*Gastrin from pyloric G cells
 
*Gastrin from pyloric G cells
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