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→Development of Bone and Cartilage
**Long bones: secondary center of ossification develops in epiphyses
**Long bones: secondary center of ossification develops in epiphyses
***'''Epiphyseal Growth Plate''': transverse disc of cartilate between the two ossification centers, allows longitudinal growth to continue to maturity, then closes
***'''Epiphyseal Growth Plate''': transverse disc of cartilate between the two ossification centers, allows longitudinal growth to continue to maturity, then closes
[[Image:Growth plate.jpg|right|thumb|100px|<small><center>Growth plate (Image sourced from Bristol Biomed Image Archive with permission)</center></small>]]
[[Image:Growth plate closer.jpg|right|thumb|100px|<small><center>Growth plate magnified(Image sourced from Bristol Biomed Image Archive with permission)</center></small>]]
***Cartilage of epiphyseal growth plate is divided into: (from right to left on the magnified image)
**** - Resting (reserve) zone
**** - Proliferative zone
**** - Hypertrophic zone
**'''Primary''' bone has not yet been '''remodelled'''
**'''Primary''' bone has not yet been '''remodelled'''
***Contains less mineral and more randomly arranged collagen fibers, trabecular organization
***Contains less mineral and more randomly arranged collagen fibers, trabecular organization