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==Porcine Juvenile Pustular Psoriasiform Dermatitis (Pityriasis rosea)==
 
==Porcine Juvenile Pustular Psoriasiform Dermatitis (Pityriasis rosea)==
   
===General===
 
===General===
 
*Pityriasis rosea is a self‑limiting inflammatory disease of young pigs.   
 
*Pityriasis rosea is a self‑limiting inflammatory disease of young pigs.   
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*The condition most frequently occurs in young pigs, 3‑14 weeks of age, and often more than one member of a litter is affected.
 
*The condition most frequently occurs in young pigs, 3‑14 weeks of age, and often more than one member of a litter is affected.
 
*'''Although this condition had been previously called pityriasis rosea, clinically and pathologically it is nothing like pityriasis rosea in humans!'''
 
*'''Although this condition had been previously called pityriasis rosea, clinically and pathologically it is nothing like pityriasis rosea in humans!'''
   
===Clinical Signs===   
 
===Clinical Signs===   
 
*There are usually no systemic signs.  Skin lesions may be preceded by anorexia, vomiting, & diarrhea.   
 
*There are usually no systemic signs.  Skin lesions may be preceded by anorexia, vomiting, & diarrhea.   
 
*There is no fever.
 
*There is no fever.
   
===Gross Lesions===
 
===Gross Lesions===
 
*Primary lesions are seen on the ventral abdomen or medial thighs, and appear as symmetric, sharply defined, red raised plaques up to 6 mm in diameter.   
 
*Primary lesions are seen on the ventral abdomen or medial thighs, and appear as symmetric, sharply defined, red raised plaques up to 6 mm in diameter.   
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**The term pseudo-ringworm has been used to describe this condition.   
 
**The term pseudo-ringworm has been used to describe this condition.   
 
*Lesions are nonirritant and usually resolve spontaneously in 2 ‑ 10 weeks.
 
*Lesions are nonirritant and usually resolve spontaneously in 2 ‑ 10 weeks.
   
===Microscopic Lesions===
 
===Microscopic Lesions===
 
*Skin biopsy reveals superficial perivascular dermatitis with psoriasiform epidermal hyperplasia.   
 
*Skin biopsy reveals superficial perivascular dermatitis with psoriasiform epidermal hyperplasia.   
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*Intra-epidermal pustules containing eosinophils and neutrophils are prominent in early lesions.   
 
*Intra-epidermal pustules containing eosinophils and neutrophils are prominent in early lesions.   
 
*Parakeratotic hyperkeratosis is usually prominent.
 
*Parakeratotic hyperkeratosis is usually prominent.
   
===Differential Diagnosis===
 
===Differential Diagnosis===
 
#Dermatophytosis ‑ (etio: Tr. mentagrophytes, M. canis, Tr. verrucosum var. discoides, M. nanum, Tr. rubrum) Ruled‑out due to lack of mycotic organisms.
 
#Dermatophytosis ‑ (etio: Tr. mentagrophytes, M. canis, Tr. verrucosum var. discoides, M. nanum, Tr. rubrum) Ruled‑out due to lack of mycotic organisms.
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#Dermatosis vegetans ‑ Systemic, erythematous maculopapular dermatitis caused by the inheritance of a autosomal recessive, semilethal factor.  Skin, coronary band and hoof lesions, giant cell pneumonia, fatal.
 
#Dermatosis vegetans ‑ Systemic, erythematous maculopapular dermatitis caused by the inheritance of a autosomal recessive, semilethal factor.  Skin, coronary band and hoof lesions, giant cell pneumonia, fatal.
 
#Swinepox ‑ Ballooning degeneration and intracytoplasmic inclusion bodies.
 
#Swinepox ‑ Ballooning degeneration and intracytoplasmic inclusion bodies.
   
===Postgraduate===
 
===Postgraduate===
 
Kate
 
Kate
 
::''IL-3 is involved... Vet Path (2007)  34: 45-43''
 
::''IL-3 is involved... Vet Path (2007)  34: 45-43''