Changes

=== Haematopoietic===

=== Haematopoietic===

<p>The haematopoietic cells produce the vast majority of blood cells in the body (haematopoiesis). In young animals this occurs in most bones in the body but in mature adults this is limited to membranous bones in the body.</p>

<p>The haematopoietic cells produce the vast majority of blood cells in the body (haematopoiesis). In young animals this occurs in most bones in the body but in mature adults this is limited to membranous bones in the body.</p>

<p>To enter circulation newly formed cells press against the sinusoid wall, temporally fusing to it and creating an opening. The cell then passes directly into the circulation and the membrane repairs itself. Mature [[erythrocytes]] immediately enter circulation, however the marrow stores leukocytes and consequently contains around ten times more [[Leukocytes - Anatomy & Physiology|leukocytes]] than found in circulation</p>

<p>To enter circulation newly formed cells press against the sinusoid wall, temporally fusing to it and creating an opening. The cell then passes directly into the circulation and the membrane repairs itself. Mature [[erythrocytes]] immediately enter circulation, however the marrow stores leukocytes and consequently contains around ten times more [[Leukocytes - WikiBlood|leukocytes]] than found in circulation</p>

<p>[[Thrombopoiesis - WikiBlood#Megakaryocyte|Megakaryocytes]] residue alongside the sinusoid membrane but do not leave the tissue, rather they release their platelets and then withdraw from the membrane.</p>

<p>[[Thrombopoiesis - WikiBlood#Megakaryocyte|Megakaryocytes]] residue alongside the sinusoid membrane but do not leave the tissue, rather they release their platelets and then withdraw from the membrane.</p>

===Lymphoid tissue===

===Lymphoid tissue===

===Others===

===Others===

*It is a significant source of antibodies as a large population of antibody-producing cells ([[B cell differentiation- Anatomy & Physiology#Plasma cells|plasma cells]]) reside in the bone marrow

*It is a significant source of antibodies as a large population of antibody-producing cells ([[B cell differentiation- Anatomy & Physiology#Plasma cells|plasma cells]]) reside in the bone marrow

*[[Macrophages - Anatomy & Physiology|Macrophages]] and dendritic cells in the marrow remove foreign substance from the blood

*[[Macrophages - WikiBlood|Macrophages]] and dendritic cells in the marrow remove foreign substance from the blood

**A process which also occurs in the [[Lymph Nodes - Anatomy & Physiology|lymph nodes]], [[Spleen - Anatomy & Physiology|spleen]] and [[Liver - Anatomy & Physiology#Functions|liver]]

**A process which also occurs in the [[Lymph Nodes - Anatomy & Physiology|lymph nodes]], [[Spleen - Anatomy & Physiology|spleen]] and [[Liver - Anatomy & Physiology#Functions|liver]]

==In pathology==

==In pathology==

*[[Bone Marrow - Pathology#Pathology|See here]]

*[[Bone Marrow - Pathology#Pathology|See here]]