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*** Not membrane associated
 
*** Not membrane associated
 
**** But binds to the α3-domain of the heavy chain
 
**** But binds to the α3-domain of the heavy chain
 +
[[Image:MHC I Structure.jpg|thumb|right|150px| Structure of MHC I molecule - Copyright Prof Dirk Werling DrMedVet PhD MRCVS]]
 
* The MHC class I domains are structurally and genetically related to immunoglobulin and TcR domains
 
* The MHC class I domains are structurally and genetically related to immunoglobulin and TcR domains
 
** The outer domains (α1 and α2) are like the variable domains
 
** The outer domains (α1 and α2) are like the variable domains
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