581 bytes added ,  16:09, 17 December 2008
m
Line 21: Line 21:     
*Present in southern Europe, Africa, Asia and South America
 
*Present in southern Europe, Africa, Asia and South America
 +
 +
*Can cause both cutaneous and visceral diseases
 +
 +
'''Recognition'''
 +
*Ovoid shaped
 +
 +
*Possesses a rod-shaped kinetoplast
 +
 +
*Has a rudimentry flagellum which does not project beyond the cell margin
 +
 +
*After the amastigote has transformed into a promastigote inside the [[Biting Flies#Psychodidae|sand fly]], the kinetoplast is situated in the posterior of the body
    
'''Life Cycle'''
 
'''Life Cycle'''
Line 37: Line 48:     
*Invades [[Macrophage|macrophages]] and reverts to amastigote
 
*Invades [[Macrophage|macrophages]] and reverts to amastigote
 +
 +
*Multiplies by binary fission
    
'''Pathogenesis'''
 
'''Pathogenesis'''
Line 48: Line 61:     
*Cutaneous form  
 
*Cutaneous form  
**Produces areas of ulceration on pinnae of ears
+
**Produces areas of ulceration on pinnae of [[The Ear - Anatomy & Physiology|ears]], eyelids or on the [[Lips - Anatomy & Physiology|lips]]
    
*Visceral form causes chronic wasting condition
 
*Visceral form causes chronic wasting condition
Line 55: Line 68:  
**Intermittent fever
 
**Intermittent fever
 
**Generalised lymphadenopathy
 
**Generalised lymphadenopathy
 +
 +
*Long periods of remission followed by the onset of clincial signs are not uncommon in infections
    
*Involved in [[Parasitic skin infections - Pathology#Protozoa|skin infections]]
 
*Involved in [[Parasitic skin infections - Pathology#Protozoa|skin infections]]
3,326

edits