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* For parturition to occur, progesterone production by the Corpus Luteum must be terminated.
 
* For parturition to occur, progesterone production by the Corpus Luteum must be terminated.
 
* As the foetus grows in a restrictive environment it becomes stressed.  Stress leades to a rise in foetal [[Pituitary_Gland_-_Anatomy_%26_Physiology#Hormones_of_the_Anterior_Pituitary_Gland|ACTH]].  The rise in ACTH causes production of Cortisol from the foetal [[Adrenal_Glands_-_Anatomy_%26_Physiology|Adrenal Glands]].
 
* As the foetus grows in a restrictive environment it becomes stressed.  Stress leades to a rise in foetal [[Pituitary_Gland_-_Anatomy_%26_Physiology#Hormones_of_the_Anterior_Pituitary_Gland|ACTH]].  The rise in ACTH causes production of Cortisol from the foetal [[Adrenal_Glands_-_Anatomy_%26_Physiology|Adrenal Glands]].
* The rise in foetal cortisol leased to an increased Oestrogen:Progesterone ratio by upregulating '''Aromatase''' enzymes which convert Androgens to Oestrogens.  Cortisol also reduces Progesterone production.
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* The rise in foetal cortisol leased to an increased Oestrogen:Progesterone ratio by upregulating '''aromatase''' enzymes which convert Androgens to Oestrogens.  Cortisol also reduces Progesterone production.
 
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=== Species that depend on Placental Progesterone===
 
=== Species that depend on Placental Progesterone===
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