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==Description==
==Description==
Hepatic lipidosis is the derangement of lipid and protein metabolism, which occurs cats and dogs, but more clinically significant in cats. It is important to differentiate primary or idiopathic hepatic lipidosis from secondary hepatic lipidosis.
Hepatic lipidosis is the derangement of lipid and protein metabolism, which occurs in cats and dogs, but more clinically significant in cats. It is important to differentiate primary or idiopathic hepatic lipidosis from secondary hepatic lipidosis.
'''Primary or idiopathic hepatic lipidosis''' is most recognised in obese indoor cats following anorexia. It is the most common hepatic disease in North America but it is also becoming more common in Europe. It is an acute hepatopathy with a large accumulation of lipid in hepatocytes, causing the liver to lose its function. The mortality rate is high unless the disease is treated aggressively. The pathogenesis includes a number of factors:
'''Primary or idiopathic hepatic lipidosis''' is most recognised in obese indoor cats following anorexia. It is the most common hepatic disease in North America but it is also becoming more common in Europe. It is an acute hepatopathy with a large accumulation of lipid in hepatocytes, causing the liver to lose its function. The mortality rate is high unless the disease is treated aggressively. The pathogenesis includes a number of factors:
'''Secondary hepatic lipidosis''' is a neuroendocrine response in dogs and cats to other diseases for example, [[Pancreatitis - WikiClinical|pacreatitis]], diabetes mellitus, [[Inflammatory Bowel Disease - WikiClinical|inflammatory bowel disease]] and primary hyperlipidaemia. Secondary hepatic lipidosis is therefore less closely correlated with obesity and be seen in normal or even thin cats.
'''Secondary hepatic lipidosis''' is a neuroendocrine response in dogs and cats to other diseases for example, [[Pancreatitis - WikiClinical|pacreatitis]], diabetes mellitus, [[Inflammatory Bowel Disease - WikiClinical|inflammatory bowel disease]] and primary hyperlipidaemia. Secondary hepatic lipidosis is therefore less closely correlated with obesity and be seen in normal or even thin cats.
==Diagnosis==
==Diagnosis==