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====Pathogenesis====
 
====Pathogenesis====
 
*Principal viral cause of '''SMEDI syndrome''': Stillbirths, Mummification, Embryonic Deaths, and Infertility
 
*Principal viral cause of '''SMEDI syndrome''': Stillbirths, Mummification, Embryonic Deaths, and Infertility
*Replicates in alimentary epithelium followed by viremia
+
*Replicates in gastro-intestinal epithelium followed by viremia
 
*Often '''no clinical signs in breeding and growing stock'''
 
*Often '''no clinical signs in breeding and growing stock'''
 
*'''Transplacental''' infection occurs in early pregnancy, with some (but not all) surviving piglets living as carriers
 
*'''Transplacental''' infection occurs in early pregnancy, with some (but not all) surviving piglets living as carriers
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