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Chloramphenicol (view source)

Revision as of 06:42, 12 November 2009

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==Pharmacokinetic Considerations==

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They are very lipophilic neutral small molecules, which are orally active and have a very wide volume of distribution. It is thus capable of penetrating cell membranes and will enter the CSF. It is eliminated in the liver via hepatic metabolism with only 10% being excreted in the urine ~~unchanges~~. The half-life varies between each species and also with age of the animal.

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They are very lipophilic neutral small molecules, which are orally active and have a very wide volume of distribution. It is thus capable of penetrating cell membranes and will enter the CSF. It is eliminated in the liver via hepatic metabolism with only 10% being excreted in the urine unchanged. The half-life varies between each species and also with age of the animal.

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==Side Effects and Contraindications==

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