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Created page with 'Gastric Ulceration - all species * Gastic ulceration is quite common in the pig- May be seen in 50-60% of pigs arriving at slaughterhouses. * Has serious economic consequence…'
[[Gastric Ulceration - all species]]
* Gastic ulceration is quite common in the pig- May be seen in 50-60% of pigs arriving at slaughterhouses.
* Has serious economic consequences.
*'''Clinical'''
** Occasionally a well-grown pig will drop dead.
*** Deep ulcers have eroded into a blood vessel, causing massive haemorrhage into the [[Forestomach - Anatomy & Physiology|stomach]] from and producing death very rapidly.
** If long standing ulcers do not result in death, they do produce pain and discomfort.
*** Give low growth rate and poor feed conversion.
*'''Pathogenesis'''
** Gastric ulceration is associated with modern pig rearing, but the exact cause is unknown.
** Causes are associated with gastric hyperacidity, and gastric ulceration is probably a multifactorial disease.
** The following are suggested as possible causes:
*** Infection, e.g. ''Candida albicans'', ''Streptococci'', ''Staphylococci'' and mixes of these.
*** Copper toxicity- this is probably more significant.
**** Pigs are fed copper as growth promoter; 50 ppm is know to be toxic, and animals are often fed 250 ppm.
*** Vitamin E / Selenium deficiency.
*** Feeding on concrete floors.
**** Sand is licked up whe pigs eat.
*** Feeding finely milled cereal.
*** Stress
*** Possibly genetic factors.
*'''Pathology'''
** Most commonly affects pars oesophagea (squamous or non-glandular portion).
** Starts with hyperkeratosis in the stratum corneum
*** Appears rough and thickened
*** May stop at this stage.
** In approximately 30% of animals, the lesion starts to erode and quite deep ulcers may develop.
** In a significant small number ,very deep ulcers develop and may affect virtually all of pars oesophagea.
** Histologically, ulcers are large and flask-shaped ulcer with fibrin, necrosis, erosion and fibrosis at base.
[[Category:Gastric_Ulceration]][[Category:Pig]]
* Gastic ulceration is quite common in the pig- May be seen in 50-60% of pigs arriving at slaughterhouses.
* Has serious economic consequences.
*'''Clinical'''
** Occasionally a well-grown pig will drop dead.
*** Deep ulcers have eroded into a blood vessel, causing massive haemorrhage into the [[Forestomach - Anatomy & Physiology|stomach]] from and producing death very rapidly.
** If long standing ulcers do not result in death, they do produce pain and discomfort.
*** Give low growth rate and poor feed conversion.
*'''Pathogenesis'''
** Gastric ulceration is associated with modern pig rearing, but the exact cause is unknown.
** Causes are associated with gastric hyperacidity, and gastric ulceration is probably a multifactorial disease.
** The following are suggested as possible causes:
*** Infection, e.g. ''Candida albicans'', ''Streptococci'', ''Staphylococci'' and mixes of these.
*** Copper toxicity- this is probably more significant.
**** Pigs are fed copper as growth promoter; 50 ppm is know to be toxic, and animals are often fed 250 ppm.
*** Vitamin E / Selenium deficiency.
*** Feeding on concrete floors.
**** Sand is licked up whe pigs eat.
*** Feeding finely milled cereal.
*** Stress
*** Possibly genetic factors.
*'''Pathology'''
** Most commonly affects pars oesophagea (squamous or non-glandular portion).
** Starts with hyperkeratosis in the stratum corneum
*** Appears rough and thickened
*** May stop at this stage.
** In approximately 30% of animals, the lesion starts to erode and quite deep ulcers may develop.
** In a significant small number ,very deep ulcers develop and may affect virtually all of pars oesophagea.
** Histologically, ulcers are large and flask-shaped ulcer with fibrin, necrosis, erosion and fibrosis at base.
[[Category:Gastric_Ulceration]][[Category:Pig]]