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Infectious Canine Hepatitis (view source)

Revision as of 15:53, 5 July 2010

379 bytes added , 15:53, 5 July 2010

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==Description==

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*adenovirus - [[Canine Adenovirus 1]]

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Infectious Canine Hepatitis (ICH) is a highly contagious disease of dogs caused by [[Canine Adenovirus 1]] (CAV1).

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*acute and ~~generalised infection~~

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*highly infectious

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Canine adenovirus 1 (CAV1) initially infects and replicates in the cells of the oropharynx, before establishing a viraemia. A tropism for endothelial cells exists, leading to attack of the liver sinusoids and the lining of the gall bladder. Kuppfer cells are also affected. This results in hepatitis.

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*spread via the ~~urine~~ of ~~infected animals over a long period of time~~

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In foxes, the virus replicates in the endothelial cells of the brain resulting in neuronal damage, fits, and paralysis.

==Signalment==

Lizzies

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