Changes

==Diagnosis==  

==Diagnosis==  

===History and Clinical Signs===

===History and Clinical Signs===

History may involve access to toxins and drugs such as [[NSAIDs|NSAIDs]]  

History may involve access to toxins and drugs such as [[NSAIDs|NSAIDs]].

Clinical Signs can include Vomiting, Haematemesis, Malaena, Pale mucous membranes, Abdominal pain, Weakness,Inappetance, Hypersalivation which can progress to circulatory compromise.

Clinical Signs can include vomiting, haematemesis, malaena, pale mucous membranes, abdominal pain, Weakness,Inappetance and hypersalivation which can progress to circulatory compromise.

===Haematology===

===Haematology===

*[[Anaemia|Anaemia]] - regenerative initially, may progress to microcytic, hypochromic and minutely regenerative.

[[Anaemia|Anaemia]] which can be regenerative initially, and may progress to microcytic, hypochromic and minutely regenerative.

A thrombocytosis may also be present. If a stress leucogram (lymphopenia and neutrophilia) is not present this is supportive of [[Hypoadrenocorticism - Addison's Disease|hypoadrenocorticism]].

*Lack of stress leucogram (and lymphocytosis and eosinophilia) supportive of [[Hypoadrenocorticism - Addison's Disease|hypoadrenocorticism]]

Examination of the buffy coat may detect mastocytosis

*Examination of the buffy coat may detect mastocytosis

[[Changes in Inflammatory Cells Circulating in Blood - Pathology#Neutrophilia|Neutrophilia]] and a left shift are indicative of inflammation or gastric perforation.

*[[Changes in Inflammatory Cells Circulating in Blood - Pathology#Neutrophilia|Neutrophilia]] and a left shift - signs of inflammation or gastric perforation

There may also be abnormalities in [[Haemostasis - Pathology|haemostasis]].

*May show abnormalities in [[Haemostasis - Pathology|haemostasis]]

===Biochemistry===

===Biochemistry===