no edit summary
Line 54: Line 54:  
Variable
 
Variable
   −
=Pathology=
+
==Pathology==
===Introduction===
+
 
    
* Inflammatory bowel disease will result in malabsorption and in many cases, chronic diarrhoea.
 
* Inflammatory bowel disease will result in malabsorption and in many cases, chronic diarrhoea.
 
* The small and/or [[Large Intestine - Anatomy & Physiology|large intestine]]s are affected.
 
* The small and/or [[Large Intestine - Anatomy & Physiology|large intestine]]s are affected.
 
** The site determines whether diarrhoea is present.
 
** The site determines whether diarrhoea is present.
* Additionally, can get extraintestinal abnormalities
+
Additionally, can get extraintestinal abnormalities including cholangiohepatitis, nephritis, pancreatitis, polyarthropathy and thrombocytopenia (uncommon).
** Cholangiohepatitis
  −
** Nephritis
  −
** Pancreatitis
  −
** Polyarthropathy
  −
** Thrombocytopenia (uncommon)
  −
*** Extent of thrombocytopenia not related to duration of IBD or  to its resolution.
  −
* The term "inflammatory bowel disease" covers several conditions characterised by the major inflammatory cell(s) present.
  −
** All have some common features:
  −
*** Thickening of the mucosa.
  −
*** Villus atrophy in advanced disease.
  −
*** Significant inflammatory infiltrate in the mucosa and sometimes deeper layers.
      +
The term "inflammatory bowel disease" covers several conditions characterised by the major inflammatory cell(s) present. All have some common features: thickening of the mucosa, villus atrophy in advanced disease and significant inflammatory infiltrate in the mucosa and sometimes deeper layers.
    +
 
==Granulomatous enteritis==
 
==Granulomatous enteritis==
   −
* Seen mainly in the dog.
+
Is seen mainly in the dog but also in the cat and horse. It is idiopathic but causes granulomatous inflammation.
** Also in the cat and horse
+
Macrophages, giant cells, [[Neutrophils|neutrophils]], eosinophils, lymphocytes and plasma cells are present.
* Idiopathic.  
  −
* Granulomatous inflammation
  −
** Macrophages and giant cells, but also [[Neutrophils|neutrophils]], eosinophils, lymphocytes and plasma cells.
      
==Idiopathic colitis==
 
==Idiopathic colitis==
1,573

edits