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==Disease==
 
==Disease==
This high incidence of infection is not matched by a  similar incidence of clinical hepatitis, and it si now known that many  infections are subclinical and that the virus is also responsible for  other conditions, e.g. encephalopathy, ocular disease, neonatal disease,  chronic hepatitis, and interstitial nephritis. In several countries,  the virus has been isolated from throat swabs or lungs from dogs with  respiratory disease, and in Britain CAV-1 is thought to be of importane  in kennel cough (infectious tracheobronchitis).
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This high incidence of infection is not matched by a  similar incidence of clinical hepatitis, and it is now known that many  infections are subclinical and that the virus is also responsible for  other conditions, e.g. encephalopathy, ocular disease, neonatal disease,  chronic hepatitis, and interstitial nephritis. In several countries,  the virus has been isolated from throat swabs or lungs from dogs with  respiratory disease, and in Britain CAV-1 is thought to be of importane  in kennel cough (infectious tracheobronchitis).
     
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