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| ** Blood '''[[Monocytes|monocytes]]''': phagocytose bacteria | | ** Blood '''[[Monocytes|monocytes]]''': phagocytose bacteria |
| ** Tissue mast cells and '''macrophages''': phagocytose bacteria | | ** Tissue mast cells and '''macrophages''': phagocytose bacteria |
− | *Effectively, innate cellular response seeks to hold off the infection until the [[Adaptive Immune System - WikiBlood|adaptive]] response can back it up with a more specific attack | + | *Effectively, innate cellular response seeks to hold off the infection until the [[Adaptive Immune System|adaptive response]] can back it up with a more specific attack |
| | | |
− | ===[[Macrophages|Macrophages]]===
| + | ==[[Macrophages|Macrophages]]== |
| [[Image:Monocytes.jpg|thumb|right|150px|Monocytes - J. Bredl, RVC 2008]] | | [[Image:Monocytes.jpg|thumb|right|150px|Monocytes - J. Bredl, RVC 2008]] |
| *The role of macrophages in Innate Immunity is to act as primary '''phagocytes''' | | *The role of macrophages in Innate Immunity is to act as primary '''phagocytes''' |
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| ** Chiefly function to replace the various tissue macrophage populations | | ** Chiefly function to replace the various tissue macrophage populations |
| | | |
− | ===[[Neutrophils|Neutrophils]]===
| + | ==[[Neutrophils|Neutrophils]]== |
| [[Image:Neutrophil 2.jpg|thumb|right|150px|Neutrophils - J. Bredl, RVC 2008]] | | [[Image:Neutrophil 2.jpg|thumb|right|150px|Neutrophils - J. Bredl, RVC 2008]] |
| * Neutrophils are the principal, highly active '''phagocytes''' in the blood | | * Neutrophils are the principal, highly active '''phagocytes''' in the blood |
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| ** Their removal from the site after the removal of infection is an important step in the resolution of the lesion | | ** Their removal from the site after the removal of infection is an important step in the resolution of the lesion |
| | | |
− | ===[[Eosinophils|Eosinophils]]===
| + | ==[[Eosinophils|Eosinophils]]== |
| [[Image:Eosinophil.jpg|thumb|right|150px|Eosinophil - J. Bredl, RVC 2008]] | | [[Image:Eosinophil.jpg|thumb|right|150px|Eosinophil - J. Bredl, RVC 2008]] |
| * Eosinophils are less common than [[Neutrophils|neutrophils]], and they are not phagocytic | | * Eosinophils are less common than [[Neutrophils|neutrophils]], and they are not phagocytic |
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| * Prominent in [[:Category:Allergic Diseases|allergic]] (anaphylactic) reactions | | * Prominent in [[:Category:Allergic Diseases|allergic]] (anaphylactic) reactions |
| | | |
− | ===[[Basophils|Basophils]] / [[Mast Cells|Mast Cells]]===
| + | ==[[Basophils|Basophils]] / [[Mast Cells|Mast Cells]]== |
| [[Image:Basophil and Lymphocyte.jpg|thumb|right|150px|Basophil - J. Bredl, RVC 2008]] | | [[Image:Basophil and Lymphocyte.jpg|thumb|right|150px|Basophil - J. Bredl, RVC 2008]] |
| * Basophils/mast cells are principally localised at epithelial surfaces | | * Basophils/mast cells are principally localised at epithelial surfaces |
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| *** Less than 0.5% circulating leukocytes | | *** Less than 0.5% circulating leukocytes |
| * They have two principal functions: | | * They have two principal functions: |
− | *# Induction of [[Inflammation - WikiBlood|acute inflammation]] | + | *# Induction of [[:Category:Inflammation|acute inflammation]] |
| *#* Trauma and/ or bacterial infection causes the production of '''cytokines''' by the mast cells that induce a classical acute inflammatory response | | *#* Trauma and/ or bacterial infection causes the production of '''cytokines''' by the mast cells that induce a classical acute inflammatory response |
| *# Response to parasite infection | | *# Response to parasite infection |