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** Blood '''[[Monocytes|monocytes]]''': phagocytose bacteria
 
** Blood '''[[Monocytes|monocytes]]''': phagocytose bacteria
 
** Tissue mast cells and '''macrophages''': phagocytose bacteria
 
** Tissue mast cells and '''macrophages''': phagocytose bacteria
*Effectively, innate cellular response seeks to hold off the infection until the [[Adaptive Immune System - WikiBlood|adaptive]] response can back it up with a more specific attack
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*Effectively, innate cellular response seeks to hold off the infection until the [[Adaptive Immune System|adaptive response]] can back it up with a more specific attack
   −
===[[Macrophages|Macrophages]]===
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==[[Macrophages|Macrophages]]==
 
[[Image:Monocytes.jpg|thumb|right|150px|Monocytes - J. Bredl, RVC 2008]]
 
[[Image:Monocytes.jpg|thumb|right|150px|Monocytes - J. Bredl, RVC 2008]]
 
*The role of macrophages in Innate Immunity is to act as primary '''phagocytes'''
 
*The role of macrophages in Innate Immunity is to act as primary '''phagocytes'''
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** Chiefly function to replace the various tissue macrophage populations
 
** Chiefly function to replace the various tissue macrophage populations
   −
===[[Neutrophils|Neutrophils]]===
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==[[Neutrophils|Neutrophils]]==
 
[[Image:Neutrophil 2.jpg|thumb|right|150px|Neutrophils - J. Bredl, RVC 2008]]
 
[[Image:Neutrophil 2.jpg|thumb|right|150px|Neutrophils - J. Bredl, RVC 2008]]
 
* Neutrophils are the principal, highly active '''phagocytes''' in the blood
 
* Neutrophils are the principal, highly active '''phagocytes''' in the blood
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** Their removal from the site after the removal of infection is an important step in the resolution of the lesion
 
** Their removal from the site after the removal of infection is an important step in the resolution of the lesion
   −
===[[Eosinophils|Eosinophils]]===
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==[[Eosinophils|Eosinophils]]==
 
[[Image:Eosinophil.jpg|thumb|right|150px|Eosinophil - J. Bredl, RVC 2008]]
 
[[Image:Eosinophil.jpg|thumb|right|150px|Eosinophil - J. Bredl, RVC 2008]]
 
* Eosinophils are less common than [[Neutrophils|neutrophils]], and they are not phagocytic
 
* Eosinophils are less common than [[Neutrophils|neutrophils]], and they are not phagocytic
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* Prominent in [[:Category:Allergic Diseases|allergic]] (anaphylactic) reactions
 
* Prominent in [[:Category:Allergic Diseases|allergic]] (anaphylactic) reactions
   −
===[[Basophils|Basophils]] / [[Mast Cells|Mast Cells]]===
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==[[Basophils|Basophils]] / [[Mast Cells|Mast Cells]]==
 
[[Image:Basophil and Lymphocyte.jpg|thumb|right|150px|Basophil - J. Bredl, RVC 2008]]
 
[[Image:Basophil and Lymphocyte.jpg|thumb|right|150px|Basophil - J. Bredl, RVC 2008]]
 
* Basophils/mast cells are principally localised at epithelial surfaces
 
* Basophils/mast cells are principally localised at epithelial surfaces
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*** Less than 0.5% circulating leukocytes
 
*** Less than 0.5% circulating leukocytes
 
* They have two principal functions:
 
* They have two principal functions:
*# Induction of [[Inflammation - WikiBlood|acute inflammation]]
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*# Induction of [[:Category:Inflammation|acute inflammation]]
 
*#* Trauma and/ or bacterial infection causes the production of '''cytokines''' by the mast cells that induce a classical acute inflammatory response
 
*#* Trauma and/ or bacterial infection causes the production of '''cytokines''' by the mast cells that induce a classical acute inflammatory response
 
*# Response to parasite infection
 
*# Response to parasite infection
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