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→Macrophage
Monocytes are incapable of mitosis and enter the circulation. They have a large kidney shaped nucleus with a slightly basophilic cytoplasm, which is often vaculoated.
Monocytes are incapable of mitosis and enter the circulation. They have a large kidney shaped nucleus with a slightly basophilic cytoplasm, which is often vaculoated.
====Macrophage====
====Macrophage====
Once the monocyte has entered tissue it differentiates into a [[Macrophages|macrophage]].
Once the monocyte has entered tissue it differentiates into a macrophage.
===Dendritic cells===
===Dendritic cells===
These develop from the monoblast under the stimualtion of GM-CSF and IL-4 into an immature dendritic cell. This then develops into the mature dendritic cell under stimulation of TNF-α.
These develop from the monoblast under the stimualtion of GM-CSF and IL-4 into an immature dendritic cell. This then develops into the mature dendritic cell under stimulation of TNF-α.