Cattle Medicine Q&A 11

This question was provided by Manson Publishing as part of the OVAL Project. See more [[:Category:{{{book}}}|{{{book}}}]].

A 6-year-old Holstein cow, which calved 36 hr earlier, is presented in sternal recumbency, profoundly depressed, dehydrated, afebrile (38.5°C,101.3°F)), with toxic mucous membranes, an elevated heart rate of 96 beats per minute, and an increased respiratory rate (34 breaths per minute). The udder is soft but a pale, serum-like, secretion can be drawn from one quarter.

Question	Answer		Article
Which diseases would you consider? (Most likely first.)	The most likely conditions to consider include: environmental (coliform) mastitis hypocalcaemia acute septic metritis other infectious conditions causing toxaemia/endotoxaemia trauma at parturition with either ruptured uterus/peritonitis or severe haemorrhage botulism It may prove difficult to rule out the possible contribution of hypocalcaemia and many clinicians would elect to administer 400 mL of 40% calcium borogluconate slowly by the intravenous route while monitoring the heart rate.		Link to Article
What treatments would you administer?	Treatment of endotoxic shock (coliform mastitis) includes intravenous injection of a NSAID, repeated 12 hr later. Hypertonic saline (7.2%) infusion at a dose rate of 5mL/kg (3 L for 600 kg cow) over 5–7 minutes is achieved through a 13-gauge 10cm jugular catheter. Access to 30–60 L of warm water, which may contain electrolytes, must be provided although not all cows drink; some clinicians recommend stomach tubing volumes up to 30–40 L. This cow made a full recovery. Mastitis caused by Streptococcus uberis can present with many of the clinical features of coliform mastitis and it may prove prudent to administer a broad-spectrum antibiotic both parenterally and by intramammary infusion.		[[|Link to Article]]
What control measures could be adopted?	Control measures include proper hygiene in the calving accommodation. Premilking teat dipping should be included in the parlour routine. Cows should be kept standing for 30 minutes after milking to enable complete teat sphincter contraction. Teat sealants should be used at drying-off. Use of J5 Escherichia coli core antigen vaccine could be considered.		[[|Link to Article]]