Skin Other - Pathology

From WikiVet English
Jump to navigation Jump to search



WikiPathWikiPath Banner.png
()Map INTEGUMENTARY SYSTEM (Map)



Epidermal growth or differentiation disorders

Seborrheic disease complex

  • Abnormal cornification or function of sebaceous glands
  • Large amounts of free fatty acids and cholesterol
  • Decreased amounts of diester waxes in surface lipids
  • Bacterial population changes to pathogenic coagulase positive staphylococci
  • Chronic disease affecting mainly dogs, sometimes cats and horses
  • Dry form - white to grey scales
  • Greasy form - scaly, excess brown to yellow lipids sticking to skin and hair

Primary idiopathic seborrhea

  • Abnormal cornification
  • Epidermal turnover reduced to about 2/3 of normal
  • Microscopically:
    • Hyperkeratosis distending follicular ostia causing papillary appearance
    • Parakeratosis at edges of follicular ostia
    • Congested, oedematous dermal papillae
    • Spongiotic epidermis with leukocytes

Secondary seborrhea

Sebaceous adenitis

Pigmentation disorders

Hypopigmentation

Hyperpigmentation

Eosinophilic infiltration

Eosinophilic plaques

Eosinophilic granulomas

Eosinophilic folliculitis and furunculosis

Sterile granulomatous disorders

Juvenile pyoderma

Equine generalised granulomatous disease