Canine X-Linked Severe Combined Immune Deficiency
Revision as of 13:55, 12 August 2010 by Bara (talk | contribs) (Created page with "(Canine SCID) *Affects Basset Hounds and Corgis *X-linked recessive defect in the gene coding for the IL-2 receptor **IL-2 receptor is a receptor for the cytokine IL-2 which caus...")
(Canine SCID)
- Affects Basset Hounds and Corgis
- X-linked recessive defect in the gene coding for the IL-2 receptor
- IL-2 receptor is a receptor for the cytokine IL-2 which causes T cells to proliferate
- Causes lymphoid hypoplasia, stunted growth and increases the animal's susceptibility to infection
- Animal usually dies from pneumonia or sepsis as the level of maternal antibody decreases