Selective IgA deficiency of German Shepherd Dogs

Description

IgA deficiency of German Shepherd dogs is a breed specific lack or reduction of immunoglobulin A caused by a heritable defect inthe immune system. Dogs which are affected are unable to mount an approapriate immune response and more susceptible to infection and alleric conditions. It has been suggested that the deficiency in IgA is linked to other disease syndromes such as deep pyoderma, inflammatory bowel disease, anal furunculosis and disseminated aspergillosis. The condition is poorly understood and the links between IgA deficiency and other conditions has not been fully documented.

Signalment

German Shepherd dogs.