Difference between revisions of "Blood Groups - Dog"

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==Introduction==
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The most widely used blood grouping system is the '''Dog Erythrocyte Antigen system (DEA)''' and within this system eight blood groups exist.
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DEA 1 (DEA 1.1 DEA 1.2), DEA2 - DEA 7.
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Often Rottweilers, Labradors and Golden retrievers have DEA 1.1 or DEA 1.2 positive blood types and Greyhounds and German Shepherd Dogs are frequently DEA 1.1 and DEA 1.2 negative. For this reason greyhounds are commonly used as donors.
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==Alloantibodies==
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Unlike [[Blood Groups - Cat|cats]] dogs do not have natural alloantibodies against other blood groups.
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There is no major risk for the first transfusion, unlike the cat, compatibility tests are not required for the dogs first blood transfusion.
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Alloantibodies form within 5-7 days of the first transfusion and consequently if a second transfusion is required 5 days later than the original transfusion compatibility tests are necessary.
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Blood typing can be carried out using commercial in house kits or can be sent away to a reference laboratory.
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Dogs can be positve for one of  DEA 1.1 or DEA 1.2 or negative for both DEA 1.1 and 1.2.
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DEA 1.1 and DEA 1.2 are the most antigenic and hence ideally a donor would be DEA 1.1 and DEA 1.2 negative.
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Transfusion reactions can occur when DEA 1.1 and 1.2 negative dogs receive DEA 1.1 or 1.2 positive blood.
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[[Neonatal Isoerythrolysis|Neonatal isoerythrolysis]] can also occur in dogs. This happens when a DEA 1.1  negative female which has previously been sensitised to DEA 1.1 positive blood is mated to a DEA 1.1 positive male.
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{| cellpadding="10" cellspacing="0" border="1"  
 
{| cellpadding="10" cellspacing="0" border="1"  
 
| See also:
 
| See also:
|'''[[Transfusion Medicine - Introduction|Transfusion Medicine - Introduction]]<br>[[Blood Collection for Transfusion|Blood Collection for Transfusion]]<br>[[Blood Groups - Cat|Blood Groups - Cat ]]'''
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|'''[[Indications for Blood Transfusions]]<br>[[Administering a Blood Transfusion]]<br>[[Blood Groups - Cat|Blood Groups - Cat ]] <br>[[Blood Groups|Blood Groups]]<br>[[Blood Products|Blood Products]]'''
 
|}
 
|}
  
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==References==
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Transfusion Therapy. Lymphoreticular and Haematology module. 4th year notes. Royal Veterinary College London. 2009.
  
The most widely used blood grouping system is the Dog Erythrocyte Antigen system (DEA)and within this system eight blood groups exist.
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'''Selected Topics in Canine and Feline Emergency Medicine'''. Volume 1. Handbook for the veterinary practitioner. ''Royal Canin''.
DEA 1 (DEA 1.1 DEA 1.2), DEA2 - DEA 7.
 
==Alloantibodies==
 
Unlike [[Blood Groups - Cat|cats]] dogs do not have natural alloantibodies against other blood groups unless a transfusion has been performed.
 
There is no major risk for the first transfusion and consequently unlike the cat compatibility tests are not required.
 
Following the first transfusion of blood, alloantibodies form within 5-7 days. If a second tranfusion is required 5 days later than the original transfusion compatibility tests are required.
 
 
 
DEA 1.1 and DEA 1.2 are the most antigenic.
 
 
 
Ideally a donor would be DEA 1.1
 
 
 
 
[[Category:Transfusion Medicine]]
 
[[Category:Transfusion Medicine]]
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[[Category:Dog - Cardiovascular System]]

Latest revision as of 16:22, 14 December 2010


Introduction

The most widely used blood grouping system is the Dog Erythrocyte Antigen system (DEA) and within this system eight blood groups exist. DEA 1 (DEA 1.1 DEA 1.2), DEA2 - DEA 7. Often Rottweilers, Labradors and Golden retrievers have DEA 1.1 or DEA 1.2 positive blood types and Greyhounds and German Shepherd Dogs are frequently DEA 1.1 and DEA 1.2 negative. For this reason greyhounds are commonly used as donors.

Alloantibodies

Unlike cats dogs do not have natural alloantibodies against other blood groups. There is no major risk for the first transfusion, unlike the cat, compatibility tests are not required for the dogs first blood transfusion. Alloantibodies form within 5-7 days of the first transfusion and consequently if a second transfusion is required 5 days later than the original transfusion compatibility tests are necessary.

Blood typing can be carried out using commercial in house kits or can be sent away to a reference laboratory.

Dogs can be positve for one of DEA 1.1 or DEA 1.2 or negative for both DEA 1.1 and 1.2. DEA 1.1 and DEA 1.2 are the most antigenic and hence ideally a donor would be DEA 1.1 and DEA 1.2 negative.

Transfusion reactions can occur when DEA 1.1 and 1.2 negative dogs receive DEA 1.1 or 1.2 positive blood.

Neonatal isoerythrolysis can also occur in dogs. This happens when a DEA 1.1 negative female which has previously been sensitised to DEA 1.1 positive blood is mated to a DEA 1.1 positive male.


See also: Indications for Blood Transfusions
Administering a Blood Transfusion
Blood Groups - Cat
Blood Groups
Blood Products

References

Transfusion Therapy. Lymphoreticular and Haematology module. 4th year notes. Royal Veterinary College London. 2009.

Selected Topics in Canine and Feline Emergency Medicine. Volume 1. Handbook for the veterinary practitioner. Royal Canin.