Difference between revisions of "Bone Response to Damage"

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<big><center>[[Bones|'''BACK TO BONES''']]</center></big>
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==Changes to normal structure==
  
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===Damage to Periosteum===
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*Invokes a hyperplastic reaction of the inner layer
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*Is painful
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*Exostoses can remodel or remain
  
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Lifting of periosteum causes new bone formation below
  
 
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Circumferential incision (e.g. during [[Bones Fractures - Pathology|fracture]])
===Normal structure===
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*Longitudinal bone growth results
 
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*May be only on one side where periosteum is damaged
**Damage to periosteum:
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**Used by surgeons to treat [[Angular Limb Deformity|angular limb deformities]]
***Invokes a hyperplastic reaction of the inner layer
 
***Is painful
 
***Exostoses can remodel or remain
 
**Lifting of periosteum causes new bone formation below
 
**Circumferential incision (e.g. during [[Bones - fractures|fracture]])
 
***Longitudinal bone growth results
 
***May be only on one side where periosteum is damaged
 
****Used by surgeons to treat [[Bones - developmental#Angular limb deformity|angular limb deformities]]
 
 
 
 
 
  
 
===Physis (Growth plate)===
 
===Physis (Growth plate)===
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*If growth teporarily stops -> layer of bone seals the growth plate -> moves into metaphysis when growth resumes -> forms '''Harris lines'''
 
*If growth teporarily stops -> layer of bone seals the growth plate -> moves into metaphysis when growth resumes -> forms '''Harris lines'''
  
===Bone resorption===
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==Test yourself with the Bone and Cartilage Pathology Flashcards==
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[[Bones_and_Cartilage_Flashcards_-_Pathology|Bones and Cartilage Flashcards]]
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*Mediated by two [[Parathyroid Pathology#Hormonal Control|hormones]]:
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[[Category:Bones - Pathology|A]]
**'''Parathyroid hormone (PTH)'''
 
***Produced by <u>chief cells in the parathyroid glands</u> in response to <u>decreased</u> serum calcium
 
***In response, osteoclasts increase in number and resorb mineralised matrix - increase Ca in blood
 
**'''Calcitonin'''
 
***Produced by <u>C-cells in the thyroid glands</u> in response to <u>increased</u> serum calcium
 
***Inhibits osteoclasts
 

Latest revision as of 12:39, 3 March 2011

Changes to normal structure

Damage to Periosteum

  • Invokes a hyperplastic reaction of the inner layer
  • Is painful
  • Exostoses can remodel or remain

Lifting of periosteum causes new bone formation below

Circumferential incision (e.g. during fracture)

  • Longitudinal bone growth results
  • May be only on one side where periosteum is damaged

Physis (Growth plate)

  • Site of many congenital or nutritional bone diseases in the growing animal
  • Open in neonates and growing animals
    • Chondrocyte proliferation balances cell maturation and death
  • Closes and ossifies at maturity
    • Regulated by androgens
  • If growth teporarily stops -> layer of bone seals the growth plate -> moves into metaphysis when growth resumes -> forms Harris lines

Test yourself with the Bone and Cartilage Pathology Flashcards

Bones and Cartilage Flashcards