Changes

[[Image:Growth plate.jpg|left|thumb|100px|<small><center>Growth plate (Image sourced from Bristol Biomed Image Archive with permission)</center></small>]]

[[Image:Growth plate.jpg|left|thumb|100px|<small><center>Growth plate (Image sourced from Bristol Biomed Image Archive with permission)</center></small>]]

[[Image:Growth plate closer.jpg|right|thumb|100px|<small><center>Growth plate magnified(Image sourced from Bristol Biomed Image Archive with permission)</center></small>]]

[[Image:Growth plate closer.jpg|right|thumb|100px|<small><center>Growth plate magnified(Image sourced from Bristol Biomed Image Archive with permission)</center></small>]]

*Originates from the cartilage model that remains only at the junction of the diaphyseal and epiphyseal centres  

*Originates from the cartilage model that remains only at the junction of the diaphyseal and epiphyseal centres  

*Cartilage of metaphyseal growth plate is divided into: (from right to left on the magnified image)

*Cartilage of metaphyseal growth plate is divided into: (from right to left on the magnified image)

** - Resting (reserve) zone

** - Resting (reserve) zone

** - Proliferative zone

** - Proliferative zone

** - Hypertrophic zone

** - Hypertrophic zone

*Site of many '''congenital''' or '''nutritional''' bone diseases in the growing animal

*Site of many '''congenital''' or '''nutritional''' bone diseases in the growing animal

*'''Open''' in neonates and growing animals

*'''Open''' in neonates and growing animals

** - Chondrocyte proliferation balances cell maturation and death  

**Chondrocyte proliferation balances cell maturation and death  

 

 

*'''Closes and ossifies''' at maturity

*'''Closes and ossifies''' at maturity

**Regulated by androgens

**Regulated by androgens