Difference between revisions of "Category:Hepatitis, Bacterial"

Revision as of 14:16, 7 June 2010

Hepatitis, Bacterial

bacteria can enter the liver through a variety of routes
- direct implantation
  - eg foreign body penetration from reticulum
- direct extension from disease in adjacent tissues of supportive peritonitis
- haematogenously
  - via the umbilical vein from an infected umbilicus
  - via the portal vein in the alimentary tract
  - via the hepatic artery in bacteraemias and septicaemias
  - via the bile ducts
the liver may show microscopic evidence of involvement in a large variety of systemic infections
these can be accompanied by jaundice
the changes in the liver are diffuse with many small areas of necrosis surrounded by neutrophils and lymphocytes
- eg Salmonellosis or Listeriosis

Content

▼ Hepatitis, Bacterial
Actinobacillus equuli
Bacillary Haemoglobinuria
Bacillary Necrosis
Infectious Necrotic Hepatitis
Leptospirosis - Cats and Dogs
Salmonellosis
Tuberculosis
Tyzzer's Disease

Bacillary Haemoglobinuria

Tyzzer's Disease

Leptospirosis - Cats and Dogs

Salmonellosis

Salmonella dublin
calves

Clinical

fever
dehydration
diarrhoea

Gross

severe, often haemorrhagic, inflammation in the ileum
paratyphoid nodules - pale foci of necrosis in the liver

Microscopically

foci of hepatocytic necrosis
mixed mononuclear inflammatory cell infiltrate

NB: small foci of hepatocytic necrosis are often found as incidental lesions at post mortem examination

Other bacteria causing liver lesions

Mycobacterium tuberculosis

in all species
causes granulomas

Actinobacillus equuli

foals
bacteria from the septicaemia localise in the liver and other tissues, including the kidney

Nocardia species

dogs
cause pyogranulomatous foci

Pages in category "Hepatitis, Bacterial"

The following 8 pages are in this category, out of 8 total.

A

Actinobacillus equuli

B

T

@@ Line 34: / Line 34: @@
-====Leptospirosis====
+====[[Leptospirosis - Cats and Dogs]]====
-*''Leptospirosis icterohaemorrhagica'' - a septicaemic disease which affects the [[Liver - Anatomy & Physiology|liver]]
-*puppies
-*Leptospirosis is an important spirochaetal group of diseases causing disease in animals and humans (zoonotic)
-*Transmission
-**via urine of affected animals
-**organisms can remain viable for weeks in damp conditions
-*method of action
-**cause anaemia via intravascular haemolysis
-=====Clinical=====
-*fever
-*dehydration
-*haemorrhaging from the mucous membranes of the body
-=====Diagnosis=====
-*dark field microscopy on fresh urine is best
-=====Gross=====
-*widespread hameorrhages
-*icterus
-*pale foci in the [[Liver - Anatomy & Physiology|liver]] (not always a constant finding)
-*subcapsular and cortical renal haemorrhages
-=====Microscopically=====
-*foci of necrosis
-*dissociation of hepatocytes form each other (similar to post mortem change)
-*substantial haemosiderin in the Kuppfer cells (from the haemolysis)
-*need to use a silver stain or immunofluorescence to demonstrate the organisms in tissues
 ====Salmonellosis====