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− | ==[[Neutrophilia]]== | + | {{frontpage |
| + | |pagetitle =Inflammation |
| + | |pagebody = |
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− | ==Neutropenia== | + | |contenttitle = Content |
| + | |contentbody =<big><b> |
| + | <categorytree mode=pages>Inflammation</categorytree> |
| + | </b></big> |
| + | |logo = |
| + | path-logo.png |
| + | }} |
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− | * Neutropenia is a reduction in numbers of [[Neutrophils|neutrophils]] circulating in the blood.
| + | [[Category:General Pathology]] |
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− | * Occurs with:
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− | ** Infections caused by Gram-negative organisms.
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− | *** Cause by the effects of their endotoxins.
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− | ** Factors that destroy their formation in the [[Bone Marrow - Anatomy & Physiology|bone marrow]].
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− | ** For example
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− | *** Radiation
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− | *** Toxins affecting bone marrow functions
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− | **** E.g. Bracken
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− | *** Some viruses
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− | **** E.g. Parvovirus and Infectious Canine Hepatitis
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− | *** Tumours that replace or displace normal [[Bone Marrow - Anatomy & Physiology|bone marrow]].
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− | ==Eosinophilia==
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− | * Eosinophilia an increase in numbers of eosinophils in the blood/tissues
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− | * Occurs in:
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− | ** Parasitism or hypersensitivity.
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− | *** The antigens of both may sensitise T-lymphocytes, and re-exposure to the agent may result in quite substantial numbers of eosinophils.
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− | ** Some breeds of dogs, e.g. German Shepherd.
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− | *** Are prone to developing eosinophilia.
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− | ==Eosinopenia==
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− | * Eosinopenia is a reduction in the number of eosinophils in the blood.
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− | * Occurs as part of the response to corticosteroids;.
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− | ** Thought to be associated with the depressive effect of corticosteroids on lymphocytes.
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− | *** Secretions of these lymphocytes are thought to stimulate eosinophil production.
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− | ==Lymphocytosis==
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− | * Lymphocytosis is an increase in numbers of lymphocytes in the blood.
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− | * Occurs:
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− | ** In tumours in which there is a substantial increase in their number.
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− | *** Some of the lymphocytes are immature - lymphoblasts.
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− | *** For example, Bovine Leukosis.
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− | ** Following adrenaline release in fear, excitement and so on.
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− | ** In some cases of chronic infection.
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− | *** However, reactive hyperplasia in associated lymph nodes may not correlate with the numbers of circulating lymphocytes.
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− | ** Commonly in growing swine.
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− | *** Possibly associated with aMycoplasma infection.
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− | ==Lymphopenia==
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− | * Lymphopenia is a redcution in the numbers of lymphocytes in the blood.
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− | * Occurs in:
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− | ** Viruses that attack the lymphoid system.
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− | *** For example:
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− | **** [[Paramyxoviridae#Canine Distemper Virus (CDV)|Canine Distemper]]
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− | **** Infectious Canine Hepatitis
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− | **** Feline Infectious Enteritis
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− | **** Bovine Virus Diarrhoea.
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− | ** Irradiation
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− | ** Corticosteroid therapy.
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− | *** Selectively suppresses lymphocytic activity, and the inflammatory response in general.
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− | *** Other immunosuppressive drugs may act in a similar way.
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− | ==Plasma Cells==
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− | * Plasma cells are rarely observed in blood.
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− | * If many plasma cells are present in blood, it is due to a plasma cell tumour that has begun to metastasise.
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− | ==Monocytosis==
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− | * Monocytosis -is an increase in numbers of [[Monocytes|monocytes]] (haematogenous macrophages) in the blood.
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− | * Occurs:
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− | ** In conjunction with neutrophilia in fear, excitement etc.
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− | ** In the chronic stages of bacterial disease.
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− | * Monocytes very rarely behave as macrophages in the blood.
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− | ** However, this is seen in cases of severe intravascular haemolysis of red blood cells where remnants of the RBC's are found in their cytoplasm.
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− | [[Category:WikiBlood]] | |