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Category:Muscles - Degenerative Pathology (view source)
Revision as of 11:53, 7 March 2011
, 11:53, 7 March 2011no edit summary
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|pagetitle =Muscles - Degenerative Pathology
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[[Image:Degenerate muscle fibres.jpg|right|thumb|100px|<small><center>Degenerate muscle fibres (Image sourced from Bristol Biomed Image Archive with permission)</center></small>]]
:'''Degeneration''':
::There are different types of degeneration and they may, or may not, be reversible. Cloudy swelling, hydropic, vacuolar, granular and fatty change all occur, following many different types of insult and are usually '''segmental'''. If [[Muscle Regeneration|regeneration]] does not occur after formation of small vacuoles, [[Muscle Necrosis|necrosis]] follows.
:Vacuolation -> floccular degeneration -> granular degeneration -> [[Hyaline Degeneration|hyaline]] and [[Zenker Degeneration|Zenker’s degeneration]] [[Hydropic Degeneration#Vacuolar Degeneration|'''Vacuolar degeneration''']]: Occurs due to swelling of organelles or due to glycogen or fat accumulation. It may be caused by hypokalaemia, hyperkalaemia or necrosis. Histologically, the cells are swollen, the section is hypereosinophilic with lost cross striations.
:'''Nutritional myopathy''': [[White Muscle Disease|White muscle disease]]
:'''Exertional myopathies''' are caused by intensive and exhaustive activity of major muscle masses. Glycogen is used up -> local heat and lactic acid -> muscle degeneration. [[Equine Rhabdomyolysis]] and [[Porcine Stress Syndrome]] are described, other forms include '''capture myopathy''', racing greyhounds, sheep chased by dogs.
:'''Neuromuscular junction diseases''': acquired [[Myasthenia Gravis]] and [[Botulism]]
:'''Circulatory disturbances''':[[Muscle Congestion|congestion]], [[Muscle Ischaemia|ischaemia]], [[Muscle Trauma|trauma]]
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<categorytree mode=pages>Muscles - Degenerative Pathology</categorytree>
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[[Category:Muscles - Pathology]]
[[Category:Muscles - Pathology]]