Gastrinoma

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Revision as of 13:41, 9 June 2010 by Bara (talk | contribs) (Created page with '[http://w3.vet.cornell.edu/nst/nst.asp?Fun=Image&imgID=7762 Image of pancreatic garstrinoma in a dog from Cornell Veterinary Medicine] *Described in dogs, cats *Known as Zollinge…')

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Image of pancreatic garstrinoma in a dog from Cornell Veterinary Medicine

  • Described in dogs, cats
  • Known as Zollinger-Ellison syndrome in humans
  • Uncommon compared to beta cell neoplasms
  • Excess gastrin causes hyperacidity in the stomach and mucosal hyperplasia of the antral region causing gastric and duodenal ulceration

Clinical signs

Pathology

  • Multiple variably sized neoplasms
  • Increased connective tissue mass - firm
  • Partiallty encapsulated
  • Invade locally
  • Metastases to liver and local lymph nodes are common