HEV express CD34 and GlyCAM-1 which bind to L-selectin on naive lymphocytes. This allows circulating lymphocytes to recognise when they have reached a secondary lymphoid organ stimulating them to leave the bloodstream and enter the lymphatic tissue. | HEV express CD34 and GlyCAM-1 which bind to L-selectin on naive lymphocytes. This allows circulating lymphocytes to recognise when they have reached a secondary lymphoid organ stimulating them to leave the bloodstream and enter the lymphatic tissue. |