Changes

===Staging===

===Staging===

A staging system is used for lymphoma (Owen, 1980):

A staging system is used for multicentric lymphoma (Owen, 1980):

* Stage I - Involvement limited to a single node or lymphoid tissue in a single organ (excluding bone marrow)

* Stage I - Involvement limited to a single node or lymphoid tissue in a single organ (excluding bone marrow)

* Stage II - Involvement of many lymph nodes in a regional area (+/- tonsils)

* Stage II - Involvement of many lymph nodes in a regional area (+/- tonsils)

* Stage V - Manifestations in the blood and involvement of bone marrow and/or other organ systems (+/-stages I-IV)

* Stage V - Manifestations in the blood and involvement of bone marrow and/or other organ systems (+/-stages I-IV)

Each stage is then subclassifed as a) without systemic signs or b) with systemic signs.

Each stage is then subclassifed as a) without systemic signs or b) with systemic signs. Other lymphomas such as primary hepatic are typically automatically classed as a grade V.

==Treatment==

==Treatment==