Difference between revisions of "Mycotoxins"

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==Hepatotoxicity==
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*metabolites of fungi
 
*metabolites of fungi
 
*'''Aflatoxins''' produced by [[Aspergillus spp.|''Aspergillus flavus'']] and other species
 
*'''Aflatoxins''' produced by [[Aspergillus spp.|''Aspergillus flavus'']] and other species
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*lesions similar to ragwort poisoning, including the hepatocytic cytomegaly
 
*lesions similar to ragwort poisoning, including the hepatocytic cytomegaly
  
[[Category:Hepatoxicity,_Chronic]]
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[[Category:Hepatotoxicity,_Chronic]]

Revision as of 22:29, 7 June 2010

Hepatotoxicity

  • metabolites of fungi
  • Aflatoxins produced by Aspergillus flavus and other species
  • main expression
    • chronic intoxication in livestock following fungal growth on badly stored (moisture) grain
  • isolated toxins
    • B1 - the most potent
    • B2
    • G1
    • G2
  • toxic intermediates bind to cellular nuclei acids and proteins
    • potent toxins, carcinogens, and teratogens (the last two are less important in domestic animals)
  • lesions similar to ragwort poisoning, including the hepatocytic cytomegaly