Difference between revisions of "Pancreas - Anatomy & Physiology"
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===Development=== | ===Development=== | ||
| − | The pancreas develops from endoderm, except for the connective tissue which develops from splanchnic mesoderm. Development begins with evaginations of the digestive tube caudal to the stomach. Two pancreatic buds form, one in the dorsal mesogastrium and one in the ventral mesogastrium. Some epithelial cells lose their connections to the developing duct system of the exocrine pancreas and develop into the islets of Langerhans of the endocrine pancreas. As the [[Forestomach - Anatomy & Physiology|stomach]] rotates, the ventral bud moves to become more dorsal. The two buds then fuse; the left lobe is derived from the dorsal bud and the right lobe from the ventral bud. The duct of the ventral lobe ('''pancreatic duct''') joins with the bile duct to form the '''common bile duct''' which opens into the duodenum at the '''major duodenal papilla'''. The duct of the dorsal lobe (accessory duct) enters the duodenum at the '''minor duodenal papilla'''. There is [[#Species Differences|species variation]] in the persistance of each duct. | + | The pancreas develops from endoderm, except for the connective tissue which develops from splanchnic mesoderm. Development begins with evaginations of the digestive tube caudal to the stomach. Two pancreatic buds form, one in the dorsal mesogastrium and one in the ventral mesogastrium. Some epithelial cells lose their connections to the developing duct system of the exocrine pancreas and develop into the islets of Langerhans of the endocrine pancreas. As the [[Forestomach - Anatomy & Physiology|stomach]] rotates, the ventral bud moves to become more dorsal. The two buds then fuse; the left lobe is derived from the dorsal bud and the right lobe from the ventral bud. The duct of the ventral lobe ('''pancreatic duct''') joins with the bile duct to form the '''common bile duct''' which opens into the duodenum at the '''major duodenal papilla'''. The duct of the dorsal lobe ('''accessory duct''') enters the duodenum at the '''minor duodenal papilla'''. There is [[#Species Differences|species variation]] in the persistance of each duct. |
==Structure== | ==Structure== | ||
Revision as of 15:18, 17 July 2008
Introduction
The pancreas has exocrine and endocrine functions. The exocrine part secretes pancreatic juice; a solution containing enzymes for carbohydrate, protein and triacylglycerol digestion. Pancreatic juice drains into the small intestine where it is functional. The exocrine part is the larger of the two parts of the pancreas. The endocrine part secretes hormones for the regulation of blood glucose concentration, including insulin, glucagon and somatostatin. The functional units of the exocrine part are the islets of Langerhans.
Development
The pancreas develops from endoderm, except for the connective tissue which develops from splanchnic mesoderm. Development begins with evaginations of the digestive tube caudal to the stomach. Two pancreatic buds form, one in the dorsal mesogastrium and one in the ventral mesogastrium. Some epithelial cells lose their connections to the developing duct system of the exocrine pancreas and develop into the islets of Langerhans of the endocrine pancreas. As the stomach rotates, the ventral bud moves to become more dorsal. The two buds then fuse; the left lobe is derived from the dorsal bud and the right lobe from the ventral bud. The duct of the ventral lobe (pancreatic duct) joins with the bile duct to form the common bile duct which opens into the duodenum at the major duodenal papilla. The duct of the dorsal lobe (accessory duct) enters the duodenum at the minor duodenal papilla. There is species variation in the persistance of each duct.
Structure
- Located in the craniodorsal part of the abdomen in close association with the duodenum.
- Divided into three parts; a body and left and right lobes.
- Generally, the portal vein runs between the left and right lobes. (see species differences).
- Rougly "V" shaped in all species.
Function
Exocrine
Endocrine
Vasculature
Innervation
Lymphatics
Histology
Species Differences
Carnivore
- Portal vein runs between the left and right lobes.
Ruminant
- Portal vein runs between the left and right lobes.
Horse
- Portal vein perforates the pancreas.
Pig
- Portal vein perforated the pancrea.