Difference between revisions of "Pneumocystis carinii"
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*It has been occasionally reported in young or immunosuppressed animals (e.g. Arabian foals with [[Equine Severe Combined Immune Deficiency|congenital immunodeficiency]]) | *It has been occasionally reported in young or immunosuppressed animals (e.g. Arabian foals with [[Equine Severe Combined Immune Deficiency|congenital immunodeficiency]]) | ||
*Grossly: | *Grossly: | ||
| − | **Diffuse [[ | + | **Diffuse [[Interstitial Pneumonia|interstitial]] [[Pneumonia Overview#Infectious causes of pneumonia|pneumonia]] |
**Patches of firmness or consolidation | **Patches of firmness or consolidation | ||
*Histologically: | *Histologically: | ||
Revision as of 18:39, 19 February 2011
- Important cause of pneumonia in humans associated with immunodeficiency states
- It has been occasionally reported in young or immunosuppressed animals (e.g. Arabian foals with congenital immunodeficiency)
- Grossly:
- Diffuse interstitial pneumonia
- Patches of firmness or consolidation
- Histologically:
- Alveoli are filled with pale staining acidophilic material (= trophozoite and cyst forms of the organism)
- It is thought that as P. carinii is often present as a latent infection, alveolar macrophages normally control the organism - a process which fails in immunodeficient states