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| ==Pathology== | | ==Pathology== |
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− | Gross necropsy lesions are minimal in the uncomplicated respiratory form of PRRS, but interstitial pneumonitis is a consistent histopathologic finding. There are no gross or histopathologjc lesions noted in aborted or stillborn fetuses. | + | Gross necropsy lesions are minimal in the uncomplicated respiratory form of PRRS. Microscopically, interstitial pneumonia is the typical finding. There is a mononuclear infiltration of the alveolar walls with type 2 pneumonocyte proliferation, and necrotic debris and macrophages accumulate in the alveolar spaces. In lymph nodes, follicular hyperplasia and necrosis may be seen. Non-suppurative meningoencephalitis and choroiditis is commonly present, but severity is highly variable. |
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− | Microscopic lesions of the fetus
| + | There are no gross lesions noted in aborted or stillborn fetuses, but histopathology inconsistently interstitial pneumonia, myocarditis anr pulmonary arteritis. However, these changes are not specific or diagnostic for PRRS. |
− | and placenta include umbilical vasculitis, interstitial
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− | pneumonia, myocarditis and pulmonary arteritis but are | |
− | inconsistent and not diagnostic for PRRS (Lager and
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− | Ackermann, 1994; Lager and Halbur, 1996; Rossow et
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− | al., 1996b). There may be residual effects of PRRS
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− | virus infection in sows manifest as a reduced conception
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− | rate (Lowe et al., 2006).
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− | | |
− | Microscopically, interstitial pneumonia
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− | with mononuclear septal infiltration, type 2 pneumonocyte
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− | proliferation and accumulations of necrotic
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− | debris and macrophages in alveolar spaces is evident.
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− | Follicular hyperplasia and necrosis may be present in
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− | lymph nodes. Nonsuppurative meningoencephalitis and
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− | choroiditis is commonly present, with highly variable
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− | severity
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| ==Control== | | ==Control== |