Difference between revisions of "Reabsorption and Secretion Along the Nephron Summary Table - Anatomy & Physiology"

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<TD BGCOLOR="#C1f0f6">'''Protein'''</TD>
 
<TD BGCOLOR="#C1f0f6">'''Protein'''</TD>
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+
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*Is reabsorbed via endocytosis
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*[[Reabsorption and Secretion Along the Proximal Tubule - Anatomy & Physiology#Protein|Link to Article]]</TD>
 
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<TD BGCOLOR="#C1f0f6">'''H<sup>+</sup> and HCO<sub>3</sub><sup>-</sup>'''</TD>
 
<TD BGCOLOR="#C1f0f6">'''H<sup>+</sup> and HCO<sub>3</sub><sup>-</sup>'''</TD>
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<TD BGCOLOR="#C1f0f6">* The secretion of H<sup>+</sup> in this section of the nephron is mainly a result of the Na<sup>+</sup>/H<sup>+</sup> antiporter in the apical membrane using secondary active transport.
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*HCO<sub>3</sub><sup>-</sup> is reabsorbed here in a different way to other substances.  The presence of hydrogen in the lumen causes some amount of it to dissociate to carbon dioxide and water via the enzyme carbonic anhydrase.  These enter the epitehlial cells where they are reformed using the same enzyme.  The HCO<sub>3</sub><sup>-</sup> then leaves the cell using the basolateral 3HCO<sub>3</sub><sup>-</sup>/Na<sup>+</sup> co-transporter.
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*[[Acid Base Balance By The Kidney - Anatomy & Physiology#Secretion of H+ and the Reabsorption of HCO3- in the Proximal Tubule|Link to Article]]</TD>
 
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<TD>'''Organic Acids and Bases'''</TD>
 
<TD>'''Organic Acids and Bases'''</TD>
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* Secreted here via primary active secretion.
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*[[Reabsorption and Secretion Along the Proximal Tubule - Anatomy & Physiology#Primary Active Secretion - Organic Acids and Bases|Link to Article]]</TD>
 
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Revision as of 12:19, 4 September 2008

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()Map REABSORPTION AND SECRETION ALONG THE NEPHRON (Map)



Substance
Proximal Tubule
Loop of Henle
Distal Tubule and Collecting Duct
Hormonal Influences
Sodium
  • Passively enters the cell via ion channels or co-transporters in the apical membrane.
  • Is pumped out of the cell via the sodium/potassium ATPase in the basolateral membrane
  • Link to Article
Potassium
  • Potassium mainly moves across the membrane via the paracellular route.
  • It is then pumped into the cell in exchange for sodium via the sodium/potassium ATPase in the basolateral membrane
  • It then leaves the cell using a co-transporter with chlorine
  • Link to Article
Urea
Water
Glucose
  • It is reabsorbed using a co-transporter with sodium via secondary active transport
  • Link to Article
Protein
Calcium
  • Bulk reabsorption but not regulation of calcium occurs in the proximal tubule
  • Link to Article
H+ and HCO3- * The secretion of H+ in this section of the nephron is mainly a result of the Na+/H+ antiporter in the apical membrane using secondary active transport.
  • HCO3- is reabsorbed here in a different way to other substances. The presence of hydrogen in the lumen causes some amount of it to dissociate to carbon dioxide and water via the enzyme carbonic anhydrase. These enter the epitehlial cells where they are reformed using the same enzyme. The HCO3- then leaves the cell using the basolateral 3HCO3-/Na+ co-transporter.
  • Link to Article
Organic Acids and Bases