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* The '''Y''' chromosome is required to '''initiate male development'''.
 
* The '''Y''' chromosome is required to '''initiate male development'''.
 
* In absence of the Y chromosome, female gonads (Ovaries) will develop.
 
* In absence of the Y chromosome, female gonads (Ovaries) will develop.
* The prime male determining gene is '''SRY''' (sex determining region of the Y chromosome.  
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* The prime male determining gene is '''SRY''' (sex determining region of the Y chromosome).  
    
* SRY is a very small piece of DNA that acts as a molecular switch to regulate structural genes and autosomal chromosomes, determining if and when they are to be activated.  
 
* SRY is a very small piece of DNA that acts as a molecular switch to regulate structural genes and autosomal chromosomes, determining if and when they are to be activated.  
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* SRY encodes the protein '''Testes Determining Factor''' (TDF)
 
* The presence of SRY alone is sufficient to ensure development of male gonads (Testes).
 
* The presence of SRY alone is sufficient to ensure development of male gonads (Testes).
 
* Female is the default sex, in absence of SRY female gonads (Ovaries) will develop.
 
* Female is the default sex, in absence of SRY female gonads (Ovaries) will develop.
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